Домой Бородавки Бородавки у детей: причины появления, что делать, как удалить, Компетентно о здоровье...

Бородавки у детей: причины появления, что делать, как удалить, Компетентно о здоровье на iLive

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Бородавки у детей на руках и ногах: причины, лечение

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Бородавки относятся к трем наиболее распространенным заболеваниям кожи, и чаще всего появляются кожные бородавки у детей и подростков.

Бородавки контагиозны, и наиболее восприимчивы к инфекции дети с их недостаточно зрелой иммунной системой.

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Эпидемиология

Кожные бородавки заразны и встречаются у 7-10% населения – независимо от возраста, но большинство случаев образования бородавок наблюдается в возрасте от 12 до 16 лет, поражая до 15-25% детей и подростков. А вот в раннем детстве они появляются крайне редко.

По статистическим данным American Academy of Dermatology, вульгарные вирусные бородавки у детей диагностируются в 10-20% случаев обращения по поводу образований на кожных покровах.

Наиболее распространенные типы бородавок у детей и подростков – плоские (на лице), подошвенные (на ногах) и обыкновенные, то есть вульгарные (на руках, локтях и коленях).

[1], [2], [3], [4], [5], [6], [7], [8], [9], [10]

Причины бородавки у ребенка

Как у взрослых, так и у детей инфекционная бородавка – небольшое, но заметное

образование, возникающее на коже некоторых частей тела – имеет одни и те же причины, которые заключаются в поражении эпидермального слоя вирусом папилломы человека (ВПЧ) семейства Papovaviridae. Более детально см. – Вирус папилломы человека

Этот тканеспецифичный ДНК-вирус распространен в коже и слизистых оболочках, и имеются косвенные доказательства того, что он живет на нашей коже и может долго сохраняться в плоскоклеточном эпителии, не вызывая никаких повреждений.

Разные штаммы (типы) ВПЧ вызывают различные виды бородавок – в зависимости от их расположения или визуальных особенностей. Например, штаммы 1, 2, 4, 27 и 57 имеют тенденцию поражать подошвы стоп, и тогда может появиться verruca plantaris – подошвенная бородавка у ребенка.

ВПЧ штамма 2 также «облюбовал» ладони рук, и при репликации его вирионов в ядра кератиноцитов кожи появляются бородавки у ребенка на руках или на пальцах. При этом типы ВПЧ 2, 7, 22 могут вызывать обыкновенные или вульгарные бородавки (verruca vulgaris).

А если появляются плоские бородавки у детей и подростков, называемые юношескими, то, скорее всего, это результат поражения кожи папилломавирусами 3, 10, 28 и 49 штамма.

По словам дерматологов, могут появляться бородавки на лице, лбу, носу, подбородке, губах, во рту у ребенка. В последнем случае, речь идет о фокальной эпителиальной гиперплазии, связанной с ВПЧ типов 13 и 32

А редкие случаи, когда выявляется ротовая папиллома или бородавка на ножке, связываются с ВПЧ типов 6, 7, 11, 16 или 32.

[11], [12]

Факторы риска

На сегодняшний день известно, что факторы риска активизации вируса папилломы человека – снижение иммунитета в связи с любой другой инфекций (к примеру, гриппом или частыми тонзиллитами), стрессом или недостаточным питанием. До сих пор считается, что важную роль в появлении бородавок играют заражение от инфицированного человека и несоблюдение личной гигиены.

Действительно, ВПЧ может выживать в течение многих месяцев и при низких температурах без хозяина; поэтому инфекционная бородавка может появиться даже после контакта с предметами, используемыми человеком с ВПЧ, а человек с подошвенными бородавками, может распространять вирус, ходя босиком.

Правда, теперь врачи убеждены: если растет бородавка у ребенка, то это свидетельство снижения функций его иммунной системы, которое проявляется в отсутствии местного иммунного ответа на ВПЧ-инфекцию, опосредованного Т-клетками.

Повышает риск роста бородавки любое повреждение кожных покровов (то есть нарушение эпителиального барьера) и их повышенная влажность (в частности, на стопах и ладонях), которые облегчают внедрение вируса в клетки эпителия.

[13], [14], [15], [16], [17], [18], [19]

Патогенез

Вирионы папилломавируса посредством рецепторного опосредованного эндоцитоза проникают в эпителиальные клетки базального слоя стратифицированного эпителия.

Из полицистронных мРНК вирус реплицируют свои геномы в ядрах инфицированных клеток-хозяев – с образованием эписомальной формы. При этом происходит активация каскада экспрессии вирусного гена, и на одну клетку образуется сразу нескольких десятков внехромосомных копий вирусной ДНК.

И патогенез обусловлен тем, что жизненный цикл ВПЧ связан с дифференциацией клеток кожи, и больше всего поражается доминирующий тип клеток в верхних слоях эпидермиса – кератиноциты, которые начинают делиться и синтезировать слишком много фибриллярного белка кератина. В результате инициированного вирусом гиперкератоза происходит постепенное локальное утолщение эпидермиса – в виде бородавки.

Согласно принятой на сегодняшней день версии, вирусные бородавки у детей образуются чаще, чем у взрослых, поскольку пролиферативные процессы в клетках кожи детей и подростков (примерно до 18 лет) отличаются повышенной активностью – под влиянием гормона роста (GH), инсулиноподобных факторов роста (IGF-1 IGF -2) и фактора роста эпидермиса (EGF), а также в связи с более высокой восприимчивостью кожных рецепторов гормона роста (IGF-1 и IGF-2), рецепторов витамина D и ядерных ретиноидных альфа- и гамма-рецепторов.

[20], [21], [22], [23]

Симптомы бородавки у ребенка

Первые признаки поражения ВПЧ эпителиальных клеток базального слоя проявляются не сразу, в среднем, в течение двух-шести месяцев. Вопреки распространенному мнению, бородавки не имеют «корней». Они растут только в верхнем слое кожи и в процессе роста могут вытеснять подлежащий слой кожи – дерму, но нее бородавки не прорастают, и их нижняя сторона гладкая.

Бородавки обычно растут из кожи в виде цилиндра, на более толстой коже таких структур, плотно прижатых друг к другу, может быть несколько, и они сливаются, придавая поверхности характерный мозаичный вид.

Вульгарные бородавки у детей имеют вид ороговевших уплотнений диаметром до одного-полутора сантиметров, которые возвышаются над поверхностью кожи. Иногда отмечаются внешние симптомы в виде крошечных черных точек в бородавке. Это вросшие в нее закупоренные свернувшейся кровью капилляры.

Бородавка может быть грубой или зернистой на ощупь, может чесаться, в некоторых случаях бородавки могут вызывать боль или распространяться на другие части тела, к примеру, возможно появление бородавки на животе.

Плоские бородавки у детей чаще всего встречаются на руках и лице; такие бородавки на руках (и тыльной стороне кистей) более гладкие, небольшого размера. Разветвленные бородавки отличаются тем, что нескольких образований на ограниченном участке кожи (часто на лице лили верхних конечностях) по форме похожи веточку или лист папоротника.

А вот бородавка на пальце у ребенка нередко может выглядеть как волдырь, но только плотный. Также бывают суб- и перигунгулярные бородавки – образующиеся под ногтем, вокруг ногтя или на кутикуле. Лечить их труднее, чем бородавки в других местах.

Подошвенные бородавки на ногах, стопе, пятке у детей обычно появляются очень плотные образования в виде бляшек желтого, серого или светло-коричневого цвета, покрытых уже упомянутыми выше черными точками. Такая бородавка из-за давления «растет» в более глубокие слои кожи; она может вызывать дискомфорт и даже быть болезненной при передвижении. Мозаичные бородавки преобладают на подошвах ног – под пальцами. Подробнее см. – Бородавки на ногах

Крайне редко диагностируется висячая бородавка или бородавка на ножке, которая может быть в виде ворсинчатого нароста около век ли губ. Второй тип удлиненных бородавок с ножкой — акрохордон или нитевидная бородавка у ребенка не образуется.

Если выросла красная бородавка у ребенка в возрасте 2-12 лет, то, скорее всего, это поражение кожи поксвирусом – вирусом контагиозного моллюска, когда обнаруживается на красном фоне белесый прыщик похожий на бородавку. Либо это может быть доброкачественная и неопасная сосудистая опухоль – гемангиома, напоминающая родинку (невус) красного цвета.

Осложнения и последствия

К счастью, бородавки не вредят здоровью детей. Но ребенок может по неосторожности повредить бородавку, например, содрать ее, тогда наиболее вероятные последствия и осложнения проявляются кровотечением и присоединение вторичной инфекции – с развитием воспаления, возможно, гнойного.

[24], [25]

Диагностика бородавки у ребенка

Бородавки идентифицируются по внешнему виду и изменению папиллярных линий кожи, которые дерматологи рассматривает при обследовании кожи пациента. Также помогает инструментальная диагностика – визуализация с использованием дерматоскопа.

Генетические методы амплификации в сочетании с генотипированием могут определять специфический тип ВПЧ, но для кожных бородавок у детей и подростков это не принципиально и не влияет на выбор терапии.

Как поводится диагностика бородавок, читайте в публикации – Бородавки: причины, симптомы, диагностика, лечение

Отличить бородавку от мозоли, себорейного кератоза, очаговой или диффузной кератодермии, эпидермального невуса, контагиозного моллюска или гемангиомы призвана дифференциальная диагностика с возможным УЗИ пораженных кожных покровов.

Также, когда бородавка у ребенка оказывается образовавшейся после рождения родинкой, которая продолжает интенсивно расти и становится более плотной, следует учитывать возможность амеланотической меланомы.

Лечение бородавки у ребенка

Плоские бородавки у детей обычно проходят самостоятельно: в течение двух лет у 40% детей (по другим данным, у 78%) без какого-либо лечения они исчезают.

Возникает вопрос: стоит ли удалять бородавки у детей? Если у ребенка не проходит бородавка, портит внешний вид или, тем более, вызывает физический дискомфорт, от нее нужно избавляться.

Какой врач лечит бородавки? Со всеми проблемами кожи, в том числе и с бородавками, нужно обращаться к дерматологу.

Как вывести бородавку у ребенка, и какие лекарства от бородавок рекомендуют дерматологи?

В первую очередь, наружно (путем смазывания бородавки с наложением пластыря) рекомендуется салициловая кислота от бородавок, действующая как эффективное кератолитическое средство. Ее нужно применять ежедневно в течение одно-двух месяцев. Препараты салициловой кислоты доступны в различных вариантах, включая гели и мази, и они часто также включают молочную кислоту, резорцин, мочевину. Полезная информация в материале – Лечение бородавок

При небольшой плоской бородавке советуют использовать карандаш с нитратом серебра (ляписом), однако нет убедительных доказательств эффективности данного средства.

Какие используют мази от бородавок у детей (Третионин, Флуороурацил и др.), подробно читайте в статье – Мази от бородавок.

Гомеопатия предлагает Cantharidin – экстракт шпанской мухи, нанесение которого на поверхность вульгарной бородавки приводит к образованию корки, вместе в которой (через некоторое время) бородавка снимается с кожи.

Чтобы убить вирус, применяются наружные противовирусные препараты (включая Имиквимод), все подробности – в материале Мази от папиллом.

В качестве системного иммуномодулирующего средства используют препарат в таблетках Левамизол (Адиафор, Декарис, Левазол, Нибутан и др. торговые названия), дозировку которого определяет врач.

Как основные средства от бородавок народное лечение включает: чеснок, репчатый лук и сырой картофель (в виде компрессов под повязку); прижигание бородавки спиртовой настойкой йода и концентрированным раствором перекиси водорода. Поскольку плоские бородавки часто встречаются на лице, рекомендуется обратиться к врачу, прежде чем использовать домашнее средство, которое может вызвать ожог кожи или оставить шрам.

А лечение травами предполагает нанесение на бородавку сока чистотела и млечного сока цветоножек одуванчика. Также читайте – Как избавиться от бородавок?

Удаление бородавок у детей обычно проводят одним из трех способов:

  • лазерное удаление бородавок, более детально, как проводят удаление бородавок лазером у детей и взрослых, см. – Удаление бородавок
  • электрокоагуляция или прижигание бородавок у детей с использованием электрического тока;
  • криодеструкция бородавок, то есть удаление бородавки у ребенка жидким азотом. Подробнее о данном методе – Удаление бородавок азотом

Профилактика

Хотя 100% гарантированного способа предотвращения бородавок нет, профилактикой может быть приучение детей регулярно мыть руки с мылом; пользоваться только своим полотенцем; носить на пляже, в бассейне, в раздевалке спортзала водонепроницаемые шлепанцы (чтобы защититься от подошвенных бородавок и других кожных инфекций).

[26], [27], [28], [29], [30]

Прогноз

Дети растут, их иммунная система становится сильнее, и бородавки у детей чаще всего проходят. Прогноз несколько омрачается тем, что они могут рецидивировать при ослаблении защитных сил организма, ведь вирус папилломы человека никуда не девается.

[31], [32], [33]

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